Brain Tissue Imaging

Safe, Low-hazard and High-rate Sectioning of Polymer Perfused Tissues.

Synopsis of project aims:

This project intends to generate the knowledge, technologies and best practices required to enable the rapid, safe and high-volume sectioning of tissues which are infused with polymers that keep the tissue chemically and morphologically stable.  The project also intends to determine:

  1. If biological particulates accumulate in the lubricants at such an amount that the liquids must be treated as hazardous waste,
  2. Which technologies minimize the creation of, and exposure to, these tissue waste products,
  3. How can the sectioning processing parameters be optimized for both sectioning as well as minimized particle generation,
  4. If this can be done without the use of lubricants, and, if not, are there environmentally friendly lubricants that can be used in tissue processing.

Project Team:

  • Hannah Gazdus
  • Yasin Hamed
  • Gillian Roerder
  • Marty Culpepper
  • Tolga Durak